There's plenty of praise and commentary on this novel already; so I will just mention just a few of my many favorite lines (even though plucking them out of context doesn't do them justice).
When the time came to leave for the synagogue, the only card my grandfather still held was to make himself disagreeable. Pick a fight and hope to be uninvited.
My grandparents forgave each other with the pragmatism of lovers in a plummeting airplane.
... a woman with a crack in her brain that was letting in shadows and leaking dreams
"That lighter," [Sally said, about a silver cigarette lighter that had belonged to his grandfather's friend in WWII, and which his grandfather had passed on to Michael].
"There was as a story behind it," [Michael replied].
"I'm sure. All of his stories were stuck behind something."